Clone Number: MRPr1
Immunogen: 168 aa amino-proximal half of protein
Concentration: 250 ug/ ml
Storage buffer: Serum free tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
Additional info: MRPr1 reacts with an epitope of MRP, a 180-195 kD transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPr1 was raised against a bacterial fusion protein of MRP, containing a segment of 168 amino acids in the amino-proximal half of the protein. MRPr1 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al. 1994).
Applications: FC, WB, ICC, IHC-fr, IHC-P (1:20-1:50)
References: Cole S et al. Science 1992; 258: 1650-1654/Flens M et al. Cancer Res 1994; 54: 4557-4563/Zaman et al. Proc Nat Acad Sci 1994; 91: 8822-8826