Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Target Synonym: ROCK 2;ROCK2;ROK alpha;ROKalpha;Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;Rock II;Rock2;Rock2m
Protein Tag: N-Sumo
Background: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Bio Activity: Not validated for activity
Sequence: Thr1212-Ser1388
Purity: > 95% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Calculated MW: 32.3 kDa
Observed MW: 38 kDa
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