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Protein Tag: N-His & C-His
Uniprot: Q8WXD2
Accession: Q8WXD2-1
Background: Member of the granin protein family that regulates the biogenesis of secretory granules.Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA.May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Bio Acitivity: Not validated for activity
Sequence: Phe20-Leu468
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Calculated MW: 51.0 kDa
Observed MW: 60 kDa
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