SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF740 conjugate, 0.1mg/mL

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker)(SDHB/2382), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC742382-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: SDHB/2382

Immunogen: Recombinant fragment (around aa 165-273) of human SDHB protein (exact sequence is proprietary)

Antibody Reactivity: SDHB

Entrez Gene ID: 6390

Antibody Application Notes: For coating for ELISA, order Ab without BSA/Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Optimal dilution and staining procedure for a specific application should be determined by user/Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
More Information
SKU BTMBNC742382-100
Manufacturer Biotium
Manufacturer SKU BNC742382-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Isotype IgG2b kappa
Host Mouse
Conjugate Conjugated, CF740
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