Target Synonym: HsT;SSCA;Member;SERPINB;serpin B;SERPINB3;HsT1196;SCC;SCCA-1;SCCA-PD;SCCA1;SSCA1;T4-A;serpin B3;Clade B(ovalbumin);Member 3;Serpin Peptidase Inhibitor;SCCA;Serpin Peptidase Inhibitor;T4-A;clade B (ovalbumin);Clade B(ovalbumin);Protein T4-A;serine (or cysteine) proteinase inhibitor;Squamous cell carcinoma antigen 1
Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Immunogen: Recombinant Human SerpinB3 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000
Calculated MW: 45 kDa
Observed MW: 45 kDa
English
Deutsch
