SJG-136, CAS 232931-57-6

Product Description: SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA. SJG-136 has potent antitumor activity.

Applications: Cancer-Kinase/protease

Formula: C31H32N4O6

References: [1]Gregson SJ, et al. Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity. J Med Chem. 2001 Mar 1;44(5):737-48./[2]Mellinas-Gomez M, et al. Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours. BMC Vet Res. 2015 Aug 19;11:215.

CAS Number: 232931-57-6

Molecular Weight: 556.61

Compound Purity: 99.47

Research Area: Cancer

Solubility: DMSO : 33.33 mg/mL (ultrasonic)

Target: ADC Cytotoxin;DNA Alkylator/Crosslinker

• SKU: MEXHY-14573-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14573-50
• Package Unit: 50 mg
• Quantity Unit: STK