Conjugation: HRP: Horseradish Peroxidase
Description of Target: STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STAG3
Key Reference: Barber,T.D., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3443-3448
Molecular Weight: 135kDa
Peptide Sequence: Synthetic peptide located within the following region:
VPHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQSProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Cohesin subunit SA-3
Protein Size: 1225
Purification: Affinity Purified
Subunit: SA-3
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