Clone Name: MSVA-740R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 32
Positive Control: Adrenal gland: A moderate to strong cytoplasmic StAR staining should be seen in the vast majority of adrenocortical cells.
Negative Control: Colon: All cells must not show any StAR staining.
Form: Liquid
Buffer (with preservative): PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]
Uniprot ID: P49675
Antigen Species: Human
Immunogen: Recombinant human STAR fragment
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: steroidogenic acute regulatory protein
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