Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2,2,4,4-tetramethyl-3,4-dihydro-2H-pyrrole 1-oxide
Purity: ≥98%
Formula Markup: C8H15NO
Formula Weight: 141.2
CAS Number: 10135-38-3
Notes: A spin trap; reacts with oxygen-, carbon-, and sulfur-centered radicals; produces longer-lived adducts than DMPO; inhibits thymocyte apoptosis induced by etoposide, 6α-methylprednisolone, or thapsigargin (IC50s = 30.7, 19.1, and 20.2 mM, respectively); has been used to monitor the formation of hydroxyl radicals in isolated rat hearts following ischemia and reperfusion