Product Description: Unguinol is a depsidone originally isolated from A. unguis. It is an inhibitor of pyruvate phosphate dikinase (PPDK; IC50=42.3 μM). It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s=8.7 and 69.5 μM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s=28.2, 50.8, and 44.3 μM, respectively).
Applications: COVID-19-immunoregulation
Formula: C19H18O5
References: [1]Stodola, et al. New depsidone from Aspergillus unguis. Phytochemistry 11(6), 2107-2108 (1972).
CAS Number: 36587-59-4
Molecular Weight: 326.34
Research Area: Infection
Target: Bacterial