UniPR1331, CAS 1809170-59-9

Product Description: UniPR1331 is a 3β-hydroxy-Δ5-choline acid derivative that inhibits Eph-ephrin interactions. UniPR1331 interacts with VEGFR2 and blocks the interaction of VEGFR2 with its natural ligand vascular endothelial growth factor and subsequent autophosphorylation, signaling, and pro-angiogenic activation of endothelial cells in vitro. UniPR1331 also inhibits tumor cell-driven angiogenesis in zebrafish[1].

Formula: C35H48N2O4

References: [1]Rusnati M, et al. Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin. Cancer Gene Ther. 2022 Jul;29(7):908-917.

CAS Number: 1809170-59-9

Molecular Weight: 560.77

Compound Purity: 96.41

Research Area: Cardiovascular Disease

Target: VEGFR

• SKU: MEXHY-123927-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123927-5
• Package Unit: 5 mg
• Quantity Unit: STK