WEHI-3773

Product Description: WEHI-3773 is an inhibitor of the interaction between VDAC2 and BAK or BAX. WEHI-3773 inhibits BAX-mediated Apoptosis by blocking the VDAC2-mediated recruitment of BAX to mitochondria. Conversely, WEHI-3773 promotes BAK-mediated Apoptosis by limiting the inhibitory sequestration of BAK by VDAC2. WEHI-3773 is promising for research in the field of anti-cancer [1].

Formula: C30H22N10O2S2

References: [1]Li K, et al. Differential regulation of BAX and BAK apoptotic activity revealed by small molecules. Sci Adv. 2025 Mar 7;11(10):eadr8146.

Molecular Weight: 618.69

Research Area: Cancer

Target: Apoptosis;Bcl-2 Family

• SKU: MEXHY-172262-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172262-0
• Package Unit: Get quote
• Quantity Unit: STK