YY-23, CAS 1365029-75-9

Product Description: YY-23 is a selective inhibitor of NMDAR (containing GluN2C or GluN2D). YY-23 inhibits GABAergic neurotransmission and enhances excitatory transmission by inhibiting NMDARs containing GluN2D on GABAergic interneurons in the prefrontal cortex. YY-23 has antidepressant activity and can be used for the research of neurological diseases[1].

Formula: C33H54O8

References: [1]Zhang J, et al. An antidepressant mechanism underlying the allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons. Sci Adv. 2025 Mar 7;11(10):eadq0444.

CAS Number: 1365029-75-9

Molecular Weight: 578.78

Research Area: Neurological Disease

Target: iGluR

• SKU: MEXHY-172261-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-172261-0
• Package Unit: Get quote
• Quantity Unit: STK