Product Description: 1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells[1].
Applications: Cancer-programmed cell death
Formula: C17H11Cl
References: [1]Peck RM, et al., Mixed bifunctionality. 4. Antitumor activity of alkylating derivatives of polycyclic aromatic hydrocarbons as a function of structure and of vehicle. J Med Chem. 1972 Jan;15(1):68-70.
CAS Number: 1086-00-6
Molecular Weight: 250.73
Compound Purity: 98.0
Research Area: Cancer
Target: DNA Alkylator/Crosslinker