Product Description: 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction[1][2].
Applications: COVID-19-immunoregulation
Formula: C23H46NO7P
References: [1]Yamamoto Y, et al. Analysis of serum lysophosphatidylethanolamine levels in patients with non-alcoholic fatty liver disease by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2021 Jan;413(1):245-254./[2]Inoue N, et al. Determination of plasma lysophosphatidylethanolamines (lyso-PE) by LC-MS/MS revealed a possible relation between obesity and lyso-PE in Japanese preadolescent children: The Hokkaido study. Ann Clin Biochem. 2025 Jan;62(1):34-45.
CAS Number: 89576-29-4
Molecular Weight: 479.59
Compound Purity: 99.0
Research Area: Infection
Solubility: DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)/Ethanol : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Drug Metabolite
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