10-Deacetyltaxol, CAS 78432-77-6

Product Description: 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc[1]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro[2]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines[3].

Applications: Cancer-programmed cell death

Formula: C45H49NO13

References: [1]19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9./[2]Michel Colin, et al. Process for the preparation of taxol and 10-deacetyltaxol. US4857653A./[3]Helson L. Cephalomannine and 10-deacetyltaxol cytotoxicity in human glial and neuroblastoma cell-lines. Int J Oncol. 1993 Feb;2(2):297-9.

CAS Number: 78432-77-6

Molecular Weight: 811.87

Compound Purity: 99.72

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Microtubule/Tubulin

• SKU: MEXHY-N1391-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N1391-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK