10-Formylfolic acid, CAS 134-05-4

Product Description: 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. 10-Formylfolic acid be used as an early indicator of leukemia[1][2].

Applications: Cancer-programmed cell death

Formula: C20H19N7O7

References: [1]M D'Urso-Scott, et al. Formation of 10-Formylfolic Acid, a Potent Inhibitor of Dihydrofolate Reductase, in Rat Liver Slices Incubated with Folic Acid. Proc Natl Acad Sci U S A. 1974 Jul;71(7):2736-9./[2]J E Baggott, et al. 10-Formyl-dihydrofolic acid is bioactive in human leukemia cells. J Nutr. 1999 Jul;129(7):1315-8.

CAS Number: 134-05-4

Molecular Weight: 469.41

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Antifolate;Dihydrofolate reductase (DHFR)

• SKU: MEXHY-124350-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-124350-5
• Package Unit: 5 mg
• Quantity Unit: STK