11β-HSD1-IN-14, CAS 946394-50-9

Product Description: 11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H20F3N3O2S

References: [1]Sun D, et al., Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). Bioorg Med Chem Lett. 2008 Jun 15;18(12):3513-6.

CAS Number: 946394-50-9

Molecular Weight: 447.47

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: 11β-HSD

• SKU: MEXHY-162026-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162026-25
• Package Unit: 25 mg
• Quantity Unit: STK