Shelf life (days): 365.0
Assay Range: 1.6-1,000 pg/ml
Sensitivity: 80% B/B0: 5 pg/ml
Cross Reactivity: 11β-Prostaglandin F2α 100%; 2,3-dinor-11β-Prostaglandin F2α 10%; 11β-13,14-dihydro-15-keto Prostaglandin F2α 0.5%; Leukotriene B4 <0.01%; Misoprostol <0.01%; tetranor-PGEM <0.01%; tetranor-PGFM <0.01%; Prostaglandin D2 <0.01%; 13,14-dihydro-15-keto Prostaglandin D2 <0.01%; Prostaglandin E2 <0.01%; 6-keto Prostaglandin F1α <0.01%; Prostaglandin F2α <0.01%; Prostaglandin F2β <0.01%; Prostaglandin J2 <0.01%; Thromboxane B2 <0.01%
Formula Weight: 0.0
Notes: 11β-PGF2α is the primary plasma metabolite of PGD2 in vivo, the levels of which can increase from 6 pg/ml in a normal healthy volunteer to 490 ng/ml in patients with systemic mastocytosis. The normal human urinary excretion of 11β-PGF2α is about 11 ng/mmol creatinine (~400 ng/24 hr), which is increased nearly 3-fold upon allergen-induced bronchoconstriction in asthmatics. Cayman’s 11β-PGF2α Assay is a competitive assay that provides accurate measurements of 11β-PGF2α within the range of 1.6-1,000 pg/ml.
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