1400W (hydrochloride), CAS 214358-33-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride

Purity: ≥98%

Formula Markup: C10H15N3 / 2HCl

Formula Weight: 250.2

CAS Number: 214358-33-5

Notes: 1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}

• SKU: CAY81520-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 81520-5
• Package Unit: 5 mg
• Quantity Unit: STK