Product Description: 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C9H8N2
References: [1]Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165./[2]Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.
CAS Number: 580-22-3
Molecular Weight: 144.18
Compound Purity: 99.95
Research Area: Infection; Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: NO Synthase;Orthopoxvirus
English
Deutsch
