2-Iodomelatonin, CAS 93515-00-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]-acetamide

Purity: ≥98%

Formula Markup: C13H15IN2O2

Formula Weight: 358.2

CAS Number: 93515-00-5

Notes: 2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}

• SKU: CAY19711-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19711-25
• Package Unit: 25 mg
• Quantity Unit: STK