2-Methoxyidazoxan (monohydrochloride) (Standard), CAS 109544-45-8

Product Description: 2-Methoxyidazoxan (monohydrochloride) (Standard) is the analytical standard of 2-Methoxyidazoxan (monohydrochloride). This product is intended for research and analytical applications. 2-Methoxyidazoxan monohydrochloride (RX821002 hydrochloride) is a highly selective alpha 2-adrenoceptor antagonist with little or no imidazoline antagonist effect. RX 821002 has markedly higher affinity for (guinea-pig) alpha 2D-adrenoceptors (pKd 9.7) than for (rabbit) alpha 2A-adrenoceptors (pKd 8.2)[1][2].

Formula: C12H15ClN2O3

References: [1]Head GA. Importance of imidazoline receptors in the cardiovascular actions of centrally acting antihypertensive agents. Ann N Y Acad Sci. 1995;763:531-540./[2]Trendelenburg AU, et al. Antagonists that differentiate between alpha 2A-and alpha 2D-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1996;353(3):245-249./[3]Sandner G, et al. Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion. Front Behav Neurosci. 2014;8:15. Published 2014 Jan 28.

CAS Number: 109544-45-8

Molecular Weight: 270.71

Research Area: Neurological Disease

Target: Adrenergic Receptor;Reference Standards

• SKU: MEXHY-103197R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103197R-0
• Package Unit: Get quote
• Quantity Unit: STK