23-hydroxy Betulinic Acid, CAS 85999-40-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (3ß,4a)-3,23-dihydroxy-lup-20(29)-en-28-oic acid

Purity: ≥98%

Formula Markup: C30H48O4

Formula Weight: 472.69972

CAS Number: 85999-40-2

Notes: 23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity.{42830} It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 µM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.

• SKU: CAY27446-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27446-10
• Package Unit: 10 mg
• Quantity Unit: STK