(2S,4S)-Sacubitril, CAS 149709-63-7

Product Description: (2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure[1][2].

Applications: COVID-19-immunoregulation

Formula: C24H29NO5

References: [1]Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9./[2]Halama A, et, al. Synthesis, Isolation, and Analysis of Stereoisomers of Sacubitril. Org. Process Res. Dev. 2019, 23, 1, 102-107.

CAS Number: 149709-63-7

Molecular Weight: 411.49

Compound Purity: 98.33

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Drug Metabolite

• SKU: MEXHY-78841-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-78841-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK