Notes: 3-Epideoxycholic acid is a secondary bile acid formed via epimerization of deoxycholic acid (DCA; Item Nos. 20756 / 18231) by gut microbiota.{54005} It has reduced detergent activity and is less active than DCA in inhibiting growth in a panel of seven gut bacteria species. 3-Epideoxycholic acid (10 and 20 µM) increases the growth of Caco-2 colon cancer cells but to a lesser extent than DCA.{49956} It increases the levels of Foxp3+CD4+ regulatory T cells (Tregs) in a co-culture of naïve T cells and dendritic cells.{49957}