3'-Hydroxygenkwanin, CAS 20243-59-8

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C16H12O6

Formula Weight: 300.26288

CAS Number: 20243-59-8

Notes: 3’-Hydroxygenkwanin is a flavonoid that has been found in B. balsamifera and has antioxidant and anticancer activities.{66019,66020} It scavenges superoxide anions in a cell-free assay when used at a concentration of 100 µM.{66019} 3’-Hydroxygenkwanin (25 and 50 µM) decreases the levels of EGFR and phosphorylated EGFR in, and reduces viability of, PC-9 and H1975 non-small cell lung cancer (NSCLC) cells.{66020} It also decreases intratumoral levels of EGFR and phosphorylated EGFR and reduces tumor growth in an H1975 mouse xenograft model when administered at a dose of 1 mg/kg.

• SKU: CAY36150-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36150-50
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe