3-Oxo-5β-cholanoic acid, CAS 1553-56-6

Product Description: 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM)[1].

Applications: COVID-19-immunoregulation

Formula: C24H38O3

References: [1]Hang S, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 Dec;576(7785):143-148.

CAS Number: 1553-56-6

Molecular Weight: 374.56

Compound Purity: 99.37

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ROR

• SKU: MEXHY-125801-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125801-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK