3-TYP, CAS 120241-79-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-(1H-1,2,3-triazol-5-yl)-pyridine

Purity: ≥98%

Formula Markup: C7H6N4

Formula Weight: 146.2

CAS Number: 120241-79-4

Notes: 3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 μM).{48840} It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used at a concentration of 10 μM.

• SKU: CAY29660-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29660-500
• Package Unit: 500 mg
• Quantity Unit: STK