(3aR)-Selitrectinib, CAS 1350884-56-8

Product Description: (3aR)-Selitrectinib ((3aR)-LOXO-195) is an isform of Selitrectinib (HY-101977), which is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and TRKA and TRKC, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C20H21FN6O

References: [1]Drilon A, et al. A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors. Cancer Discov. 2017 Sep;7(9):963-972.

CAS Number: 1350884-56-8

Molecular Weight: 380.42

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Trk Receptor

• SKU: MEXHY-101977B-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101977B-1
• Package Unit: 1mg
• Quantity Unit: STK