4-CPPC, CAS 29553-70-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid

Purity: ≥95%

Formula Markup: C14H9NO6

Formula Weight: 287.2244

CAS Number: 29553-70-6

Notes: 4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.

• SKU: CAY30068-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30068-1
• Package Unit: 1 mg
• Quantity Unit: STK