4E-BP1/EIF4EBP1 Monoclonal Antibody

Target Synonym: 4EBP;eIF4E binding protein;eukaryotic translation initiation factor 4E-binding protein;4E-BP;EIF4EBP;EIF4EBP1;4E-BP1;4EBP1;BP-1;PHAS-I;eukaryotic translation initiation factor 4E-binding protein 1;BP 1;eIF4E binding protein 1;eIF4E-binding protein 1;PHASI;Phosphorylated heat- and acid-stable protein regulated by insulin 1;4EBP1;4E-BP1;BP-1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I

Background: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen: Recombinant Human 4E-BP1 / EIF4EBP1 Protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: WB 1:500-1:1000;ICC/IF 1:100-1:500;

Calculated MW: 13 kDa

Observed MW: 13 kDa

• SKU: ELSAN200088P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN200088P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated