5-Ethynyl-2’-deoxyuridine, CAS 61135-33-9

DNA labeling agent

CAS No.: 61135-33-9.

Molecular Formula: C11H12N2O5.

Molecular Weight: 252,2.

Source: Synthetic.

Purity: >98% (HPLC); NMR (Conforms).

Solubility: May be dissolved in DMSO (10 mg/ml).

Appearance: Off-white powder.

PubChem CID: 472172.

Scientific Background: 5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor DNA synthesis through click chemistry (1). Unlike 5-bromo-2’-deoxyuridine (BrdU), EdU does not require sample fixation or DNA denaturation. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.

References: 1. Salic A., and Mitchison, T.J. (2008) Proc. Natl. Acad. Sci. USA. 105:2415.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-597-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-597-50MG
• Package Unit: 50 mg
• Quantity Unit: STK