5-fluoro 203, CAS 260443-89-8

Description: 5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

CAS Number: 260443-89-8

Formula: C14H11FN2S

Molecular Weight: 258,31

References: Mclean L S , Watkins C N , Campbell P , et al. Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells[J]. Chemical Research in Toxicology, 2015, 28(5):855-71.

• SKU: TGMT21704-200mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T21704-200mg
• Package Unit: 200 mg
• Quantity Unit: STK