5-Hydroxytoluene-2,4-disulphonic acid (diammonium)

Product Description: 5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].

Applications: COVID-19-anti-virus

Formula: C7H14N2O7S2

References: [1]Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.

Molecular Weight: 302.33

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Virus Protease

• SKU: MEXHY-136573-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136573-100
• Package Unit: 100 mg
• Quantity Unit: STK