Product Description: 5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C46H56N7O9P
References: [1]Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839./[2]Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81./[3]Vasquez G, et al., Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839.
CAS Number: 945628-66-0
Molecular Weight: 881.95
Compound Purity: 98.89
Research Area: Cardiovascular Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Nucleoside Antimetabolite/Analog
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