5-Ph-IAA, CAS 168649-23-8

Product Description: 5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression[1].

Applications: Cancer-programmed cell death

Formula: C16H13NO2

References: [1]Aisha Yesbolatova, et al. The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. Nat Commun. 2020 Nov 11;11(1):5701.

CAS Number: 168649-23-8

Molecular Weight: 251.28

Compound Purity: 99.62

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain

• SKU: MEXHY-134653-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134653-25
• Package Unit: 25 mg
• Quantity Unit: STK