5HPP-33, CAS 105624-86-0

Product Description: 5HPP-33 is an inhibitor for tubulin polymerization with IC50 of 8.1 μM. 5HPP-33 inhibits the proliferation of leukemia cell and multiple myeloma cells with IC50 of 1-10 μM, arrests the cell cycle at G2/M phase, and induces apoptosis[1][2].

Applications: Cancer-programmed cell death

Formula: C20H21NO3

References: [1]Inatsuki S, et al. Tubulin-polymerization inhibitors derived from thalidomide. Bioorg Med Chem Lett. 2005 Jan 17;15(2):321-5. /[2]Iguchi T, et al. 5HPP-33, a Novel Tubulin-Polymerization Inhibitor Derived from Thalidomide, Directly Inhibits Proliferation and Induces Apoptosis of Human Multiple Myeloma Cells[J]. Blood, 2005, 106(11): 1586.

CAS Number: 105624-86-0

Molecular Weight: 323.39

Research Area: Cancer

Target: Apoptosis;Microtubule/Tubulin

• SKU: MEXHY-114545-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-114545-10
• Package Unit: 10 mg
• Quantity Unit: STK