Shelf life (days): 730.0
Formulation: A solid
Formal Name: 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
Purity: ≥95%
Formula Markup: C20H20O5
Formula Weight: 340.3698
CAS Number: 68682-01-9
Notes: (±)-6-Prenylnaringenin ((±)-6-PN) is a flavonoid that has been found in the hop plant, H. lupulus, and has diverse biological activities.{64052,64054} It inhibits the T-type voltage-gated calcium (Cav) channel Cav3.2 and high-voltage-activated calcium currents in whole-cell patch-clamp assays using HEK293 cells (IC50s = 0.912 and 4.765 µM, respectively).{64052} It inhibits proliferation of PC3 and DU145 prostate cancer cells (IC50s = 18.4 and 29.1 µM, respectively).{64054} (±)-6-PN (20 and 30 mg/kg) reduces mechanical allodynia in a mouse model of neuropathic pain induced by partial sciatic nerve ligation.{64052}
English
Deutsch
