Product Description: 7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis[1][2].
Formula: C17H20Cl2N2OS
References: [1]Meltzer H Y, et al. Effect of metabolites of chlorpromazine on plasma prolactin levels in male rats[J]. European Journal of Pharmacology, 1977, 41(4): 431-436./[2]Perry T L, et al. 7-Hydroxychlorpromazine: potential toxic drug metabolite in psychiatric patients[J]. Science, 1964, 146(3640): 81-83.
CAS Number: 51938-11-5
Molecular Weight: 371.32
Research Area: Neurological Disease
Target: Dopamine Receptor;Drug Metabolite
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