8-Chloro caffeine, CAS 4921-49-7

Product Description: 8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine[1][2].

Formula: C8H9ClN4O2

References: [1]Nilsson K, et al. The effect of methylated oxypurines on the size of newly-synthesized DNA and on the production of chromosome aberrations after UV irradiation in Chinese hamster cells. Mutat Res. 1975 Nov;30(2):255-66. /[2]Bruns RF. Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts. Biochem Pharmacol. 1981 Feb 15;30(4):325-33.

CAS Number: 4921-49-7

Molecular Weight: 228.64

Research Area: Cancer

Target: Adenosine Receptor

• SKU: MEXHY-W178327-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W178327-0
• Package Unit: Get quote
• Quantity Unit: STK