8-hydroxy Efavirenz, CAS 205754-33-2

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

Purity: ≥98%

Formula Markup: C14H9ClF3NO3

Formula Weight: 331.674109

CAS Number: 205754-33-2

Notes: 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz (Item No. 14412).{49116} 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.{49117}

• SKU: CAY27853
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27853-1
• Package Unit: 1 mg
• Quantity Unit: STK