A-395, CAS 2089148-72-9

Product Description: A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM[1].

Applications: Neuroscience-Neuromodulation

Formula: C26H35FN4O2S

References: [1]He Y, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017 Apr;13(4):389-395.

CAS Number: 2089148-72-9

Molecular Weight: 486.65

Compound Purity: 99.12

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Histone Methyltransferase

• SKU: MEXHY-101512-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101512-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK