A-484954, CAS 142557-61-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine-6-carboxamide

Purity: ≥98%

Formula Markup: C13H15N5O3

Formula Weight: 289.2901

CAS Number: 142557-61-7

Notes: A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K; IC50 = 420 nM).{51146} It reduces eEF-2K autophosphorylation in PC3, HeLa, H460, H1299, and MDA-MB-231 cancer cells when used at a concentration of 75 μM.

• SKU: CAY28279-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28279-10
• Package Unit: 10 mg
• Quantity Unit: STK