A-966492, CAS 934162-61-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[2-fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide

Purity: ≥98%

Formula Markup: C18H17FN4O

Formula Weight: 324.352343

CAS Number: 934162-61-5

Notes: A-966492 is a dual inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (Kis = 1 and 1.5 nM, respectively).{54041} It reduces tumor growth by 46 and 92% in an MX-1 mouse xenograft model when administered at doses of 100 and 200 mg/kg per day, respectively.{54041} A-966492 also reduces tumor growth in a B16/F10 murine melanoma model when administered in combination with temozolomide (Item No. 14163).

• SKU: CAY26378-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 26378-10
• Package Unit: 10 mg
• Quantity Unit: STK