Product Description: α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes[1][2][3][4].
Applications: Neuroscience-Neuromodulation
Formula: C12H16O7
References: [1]Avonto C, et al. Comparative studies on the chemical and enzymatic stability of alpha- and beta-arbutin.Int J Cosmet Sci. 2016 Apr;38(2):187-93./[2]Saeedi M, et al. A comprehensive review of the therapeutic potential of α-arbutin. Phytother Res. 2021 Aug;35(8):4136-4154. /[3]Sugimoto K, et al. Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. Biol Pharm Bull. 2004 Apr;27(4):510-4./[4]Hazman Ö, et al. Two faces of arbutin in hepatocellular carcinoma (HepG2) cells: Anticarcinogenic effect in high concentration and protective effect against cisplatin toxicity through its antioxidant and anti-inflammatory activity in low concentration[J]. Biologia, 2022, 77(1): 225-239.
CAS Number: 84380-01-8
Molecular Weight: 272.253
Compound Purity: 99.98
Research Area: Cancer; Metabolic Disease; Neurological Disease
Solubility: H2O : 125 mg/mL (ultrasonic)
Target: Tyrosinase
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