AA43279, CAS 354812-16-1

Product Description: AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model[1].

Formula: C12H12N2O2S

References: [1]Frederiksen K, et al., A small molecule activator of Nav 1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission in vitro and has anti-convulsive effects in vivo. Eur J Neurosci. 2017 Aug;46(3):1887-1896.

CAS Number: 354812-16-1

Molecular Weight: 248.31

Compound Purity: 98.0

Research Area: Neurological Disease

Target: Sodium Channel

• SKU: MEXHY-125928-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125928-100
• Package Unit: 100 mg
• Quantity Unit: STK