AB-680, CAS 2105904-82-1

Product Description: AB-680 is a highly potent, reversible and selective inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity[1].

Applications: Cancer-programmed cell death

Formula: C20H24ClFN4O9P2

References: [1]Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

CAS Number: 2105904-82-1

Molecular Weight: 580.82

Compound Purity: 99.71

Research Area: Cancer

Solubility: DMSO : 200 mg/mL (ultrasonic)/H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: CD73

• SKU: MEXHY-125286-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125286-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK