Abemaciclib metabolite M2, CAS 1231930-57-6

Product Description: Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity[1][2].

Applications: Cancer-Kinase/protease

Formula: C25H28F2N8

References: [1]Teresa Burke, et al. Abstract 2830: The major human metabolites of abemaciclib are inhibitors of CDK4 and CDK6. Cancer Research. July 2016, 76 (14)./[2]CHMP. Assessment report Verzenios. 26 July 2018 EMA/551438/2018.

CAS Number: 1231930-57-6

Molecular Weight: 478.54

Compound Purity: 99.94

Research Area: Cancer

Solubility: DMSO : 2 mg/mL (ultrasonic)

Target: CDK;Drug Metabolite

• SKU: MEXHY-128669-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128669-50
• Package Unit: 50 mg
• Quantity Unit: STK