Product Description: Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump (H+-ATPase) and leads to the plasma membrane depolarization in a Ca2+-dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C15H20O4
References: [1]Mathias Brault, et al. Plasma membrane depolarization induced by abscisic acid in Arabidopsis suspension cells involves reduction of proton pumping in addition to anion channel activation, which are both Ca<sup>2+</sup> dependent. Plant Physiol. 2004 May;135(1):231-43./[2]Andrew Leber, et al. Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle. Sci Rep. 2020 Jun 26;10(1):10463.
CAS Number: 21293-29-8
Molecular Weight: 264.32
Compound Purity: 99.72
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 1.25 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Endogenous Metabolite;Proton Pump
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